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Consistent with platelet aggregation, OroA (100 M) inhibited IIb3 activation and CD62P expression after different agonist stimulation, suggesting that OroA could reduce inside-out signaling to modulate platelet activation (Fig

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Potential insulin sensitivity changes While no direct evidence suggests a negative effect on blood sugar, some peptides may affect insulin signaling over time

The gut microbiota metabolite propionate ameliorates intestinal epithelial barrier dysfunction-mediated Parkinsons disease via the AKT signaling pathway

The quantification of the total amounts of succinate and malate was performed employing a Bruker Advance UHPLC system coupled to ESI-MS/MS (EVOQTQMS) for chromatographic separation, fragmentation and quantification as described in Larsen ( Larsen, T.M